I was giving my 70 lb golden doodle Trifexus, for nearly 2 years until suddenly he refused to eat it. Will never use again. Not grass grazing either. Simparica Trio Recall can be trusted with their product. I removed it immediately She just tested positive for Lyme's. I gave simparica trio to my 10-year-old Havanese. My nearly 14 year old Havanese Kokomo has taken a sharp decline in the last 8 month and I was blaming it on old age when I think I may have been poisoning him. Hey carol im so sorry to hear about your dog? Im petrified after reading the comments here. She has been taking the medicine since she was 6 months and she has gotten bigger so her dosage was increased. I will keep a close eye on him and hopefully nothing else come about, we will NEVER take this medication again! Buy Simparica Trio Chewable Tablet for Dogs, 44.1-88 lbs, (Green Box), 12 Chewable Tablets (12-mos. Simparica has possibly shown no severe side effects that may concern the health of dogs. Those with Diarrhea symptom, did it look like mucus in their pets stool? The leaflet inside at least needs to be changed to have the correct information on it. Follow the directions on the drug label for Simparica or Simparica Trio or as provided by your veterinarian. Im wondering if anyone else has seen these types of symptoms. Side effects include: vomiting, diarrhea, lethargy, anorexia, otitis externa (ear. This class has been associated with neurologic adverse reactions including tremors, ataxia, and seizures. I'm more concerned about fleas and heartworms and Trifexis is just fine for that. Millions of dogs take flea and heartworm meds without side effects but that's not to say it doesn't happen or that an alternative would be safer. We did not make the connection until today. She has good days and bad days but she is far from the dog she use to be. Simparica Trio does cover more but after reading both I've decided to use Revolution. I took him in today and they think it might be meningitis. She is only 6 and was so full of life and energy. Simparica Trio is just one of many parasite prevention products on the market for dogs. Head bobbling and hind legs unable to support her - as if she were really drunk. This drug needs to be pulled off the market! He is not the same puppy prior to two days ago! I hope it has no permanent impact on him. Other specific monitoring or routine testing while your pet is on this medication may be recommended by your veterinarian depending on your pet's individual needs. The only thought in my head was to get home and give it to my puppy who has had few fleas, but many itching problems. Our 3 mo.old Boston Terrier, 10 lbs, had her first dose of Simparaco yesterday. Is your dog still having tremors? I am hopeful he will make it through the next few weeks. Called his vet and they gave no information. If most side effects are mild, ( vomiting 12 hours later could be due to other things the dog has eaten within those 12 hours), I am ok with that. Then suddenly dog has diarrhea and it lasted for several days. In such cases, please visit the veterinarian as soon as possible. Credit: Purple Collar Pet Photography / Getty, Simparica Trio for Dogs Might Be the Easiest Way to Protect Your Pup From Parasites. Some years back my husband gave vet approved & sold oral flea/tic medication to each of our 2 Standard Poodles. This is terrible. I'm just so angry that the vet prescribed this and I am mad at myself for not researching it. I thought the first one it happened to may have gotten something in her eye but then a few days later the other had the same issue. Currently, for Simparica, less than 0.01% of dogs taking this medication have experienced any neurologic side effects. My personal dog has had no issues at all, and she's been on it for nearly two years. We go for more bloodwork today and are praying for better news. She also started drinking excessively, and peeing in the house. I just started my 80 pound pit on this same medication yesterday. Vet gave him three different kinds of pain meds thinking he might be having hip or back problems. Needless, to say I will not be giving them the simparica trio again. We gave our one year old Simparica tonight and he started having trimmers that lasted on and off for about 30 minutes. If not, we had some success with symptom management using Prednisone. We all want to protect our pets from fleas, ticks and the diseases they carry, but some treatments can come with nasty side effects. In clinical trials, vomiting and diarrhea were the most frequently reported adverse reactions. I realized it was from the simparica. If she had just taken it they could give her Charcoal. Zoetis (Simparica, Simparica Trio, Revolution Plus): 888-963-8471; If you prefer to report directly to the FDA, or want additional information about adverse drug experience reporting for animal drugs, see How to Report Animal Drug and Device Side Effects and Product Problems. The risk and consequences of tick paralysis are much higher than the risk of side effects. She spent 4 nights at the University of Auburn emergency room and vet clinic. So, again, tears in my heart, THANK YOU ALL SO MUCH for your generous information. Hoping we dont have any more issues and will not be giving this again. No more itching but covered in same scabs. But anyways - the other night , his feet collapsed from under him & he fainted . Weighing your dog regularly will ensure that you are using the correct product size. This has gone on for about half of the day. But few people read it or think it must be a million to one problem. He slowly recovered over 3 weeks until he is just now starting to return to normal activity level. She passed away soon after taking this medication. I went and picked her up today and all she does is lay around and drink water, turns her nose up at anything food related. We have given him pedialyte. I hope this product is no longer sold anywhere. I put water with electrolytes by his cage & food . However a spinal tap of the fluid surrounding the spinal cord would be need to prove your dog indeed has spinal meningitis and then to treat for the specific bacterium or viral causes. I gave my six-year-old dog SIM perica because the combo guard was on back order. How can you give a dog a pesticide to ingest. Sarolaner, one of the ingredients in SIMPARICA TRIO, is a member of the isoxazoline class. Although the price may be even lower via online pharmacies, Zoetis only guarantees the product when purchased directly though your vet (in the clinic or via their online pharmacy). But now I tell everyone just be aware that this product does have the potential to cause neurological harm. I returned that medicine back to the vet and bought Revolution! I'm not going to make her a test case by giving her another dose next month. The exact same thing is happening to my dog now. How is your puppy doing? Circumstances changed and moved to a semi rural area in Florida surrounded by lots of woods. I will NEVER give this drug to my dogs! That night he seemed a little uncomfortable, unable to sleep, and I didnt think anything of it. She was ok for awhile, then she had a seizure and started throwing up all over the house. Does any one think this could be a reaction to Simparico Trio? Not wanting to play, shivering, and drinking excessively. The Simparica chewable is a poor choice for dogs with a history of prior seizures. I am hoping it is almost all out of her system. Thursday morning was an awful beginning of the day for our boy. He is just laying in his crate . Please advise! I thought right away it must be the new meds! It is important to work with your veterinarian to ensure the best flea/tick and heartworm prevention plan for your pets specific needs. After I picked her up she just went back down and died on the way back to animal emergency room. What number do we call for FDA? before i even gave to my dog small doxie i asked the vet about it and they assured me it was safe since she was and i say was a healthy dog. Could this be caused by the med? best of luck to all whose furry ones have gotten sick from this and as well hugs to those who lost their beloved pets. The FDA continues to monitor adverse drug event reports for these products and encourages pet owners and veterinarians to report adverse drug events. Hi, how much charcoal did you administer? He is very whinny and is drinking a lot of water. For me, Simparica Trio has made parasite control effective and easyI just give her one chewable tablet each month. I am a physical therapist, and acquired Sadie to serve as a Therapy Dog in our clinic. If this is a long term issue, I doubt they would be willing to cover all visits in the future. Nexgard can cause lethargy and a loss of appetite in dogs. Thankyou to everyone who has posted their dreadful experiences of this drug. She was due to get the next dosage this week and i am choosing not to give it to her with the hopes that it will be out of her system and her Liver levels will go down. It is Now 3 pm and Lily is on her way to the animal hospital and most likely going to have to spend the night, we will flush her with iv and hope It helps Flush It out Of her system. Gave my 12 year old labradoodle simpatico just before going to my sons for T-Day dinner. My vets comment was I would know if his symptoms were related if at time for next dose his symptoms were gone they are gone. not eating alor and wants me to rub her tummy constantly . I gave my 15 year old dog this medicine. He has been getting groomed since he was 3 months old but we've noticed that he has been getting more anxious with time. She became very neurotic, so many changes in her personality and she became very anxious her first and only dose was in November 2020 she never returned to the special dog that we had and she passed in March 2021 at 8 years old. I came across this site and read so much about symptoms that I now realize he has been having. Is Simparica only available with a prescription? I lost my girl 2 days after taking Simparica. Simparica Trio is not effective against adult heartworms. Eyes roll back. You ask why they are giving this poison to our furbabies, it's easy. I realized he had no control over his body . 24 hours later she had another one. 100% effective, zero side effects. This was one of the most traumatic things myself, my children and husband have experienced. Were now into day 2 no changes except add a continuous walking into the next room turn around come back sit down just to repeat several more times. I have a chihuahua/miniature pincher mix dog thats 9 yrs. What are the side effects of simparica trio for dogs? I wish I would have seen this conversation before giving my 8 year old Labrador Retriever his first dose of Simparica Trio on Wednesday March 31st! I am so angry. Our golden retriever had his first seizure after taking Simparica Trio last October. The older of the 2 Poodles seemed to do fine but my younger Poodle who was about 3 years old was definitely affected and we had a difficult time even getting him to eat for at least 2 weeks. Back to the vet and I hope they credit my money. How can it not be the Simparica that did this to my baby when nothing else changed. Never happened before. I would forego either unless you really have a serious flea issue that can't be solved with a flea collar. My 14 year old, 3.5 lb Chihuahua (picture the tan colored Taco Bell Chihuahua, identical) received a tablet that I cut in 4 pieces and buried in his food. If your dog has reactions to this medicine, push fluids! She had the treatment yesterday and seemed ok. He did blood work and found that the phosphorus levels in her blood were way to low and that was causing the neurogical problems and it was most likely from Simparica Trio. Simparica is pretty new in England and it seems they are trialling it. Each tablet is formulated to provide minimum dosages of 0.54 mg/lb (1.2 mg/kg) sarolaner, 0.011 mg/lb (24 g/kg) moxidectin, and 2.27 mg/lb (5 mg/kg) pyrantel (as pamoate salt). Other signs may include: Lethargy Loss of appetite This is whats happening to our pup, can you please tell me how long it lasted? Heal quickly and clumps of hair fall out. Insurance for dogs, cats, and other household animals can run as low as $20 a month, but that cost can add up over time. I am SOOO angry! My dog was super sick the first months of his life. I did find another one in New Hampshire but I know like everyone else that all we be negative just like all tests done so far. Best of luck. She's finally resting at home, but still not able to walk, run, eat, etc. I finally got him to eat some chicken and he threw that up 2 hours later. I've sent this thread and loads of other information to my vet and zoetis. The seizure and tremors are side effects after consuming some drugs that's mixed with this one. Hi, Im having similar issues. Only some dogs show this symptom. Tick titer came back a light positive which lab said was specifically false due to the recent lyme x2 booster i was scared in to giving. He is a 89 lbs 5 y/o pitbull who has never had any issues before. Chewable tablets can be given directly to your dog or broken up and mixed with food. #JusticeforCassie My thoughts and prayers are with you all as I go through the same thing with my beautiful Cassie girl. I am also very worried about him. I will never give this again! I am so worried after reading these comments. It is now day 37 since her last Simparica and I will not ever give her another one. He eats and drinks fine but looks like we havent fed him in days. My husband said that he felt like it would just make his coat shiny. Skin issues. I also changed him over to a raw diet a few weeks ago too have taken him off of this again to see if raw diet is causing it. Any believers out there please say a prayer for our pup as I will for the people on this thread. In a well-controlled laboratory study, SIMPARICA TRIO began to kill fleas at 4 hours and demonstrated 100% effectiveness at 8 hours after initial administration. CET Enzymatic Oral Hygiene Chews for Dogs. My 15 yr old doodle wasnt given bravecto because of reviews. Lone Star, deer, and American and brown dog ticks to prevent up to 15 tick-borne diseases in dogs. This excerpt is from the healthline website and in reference to humans "GABA is considered an inhibitory neurotransmitter because it blocks, or inhibits, certain brain signals and decreases activity in your nervous system. Do you think that Simparica could cause excessive licking by my dog. This medication should be banned and the company held responsible. My baby is so sick from this Drug. He had a problem with severe biting a few months back and Vet said he most likely allergic to fleas (bites). I wish I could get this out of her system now. Pyrantel only treats parasites found in the gastrointestinal tract because it does not absorb well into the bloodstream. It is a very traumatic experience that I saw my 1 year old dog go through and now no lo ever here. Your veterinarian may recommend a heartworm test if you are using Simparica Trio. It hurts to see this and infuriating to know these stories are out here and we did not do the research before giving our little guys this poison. When he lays in the sun you can see the bumps under his skin. My 8 month old labradoodle has had 2 doses of Simparico Trio. Vets at Petsmart should know better; changing vets. Has anyones dog stopped having seizures when the medication wore off or is this going to be a permanent issue possibly getting worse? Contrary to the statement in that same above article "The results are fatal for fleas and ticks but safe for mammals such as your dog." Snores like a big dog. Other adverse reactions like lethargy, anorexia, itching, and increased thirst are possible but not very likely. By the following day, she was showing symptoms of marked neurological impairment, similar to a human having suffered a stroke. She wanted me to monitor him carefully and wait to see how he did on his next dose of Simparica before continuing to prescribe it. Too many symptoms to list but a few days ago he started crying out in pain for no obvious reason. He has horrible water like stools. She will never have this again, I can assure you! My Irish setter is weak on her left side, left side of her face is drooping and she now carries her head with a tilt to the left. Simparica Trio should be given orally once a month at the recommended minimum doses: 0.54 milligrams of sarolaner, 0.011 mlilligrams of moxidectin, and 2.27 milligrams of pyrantel per pound of body weight. These include vomiting, diarrhea, lethargy, inappetence, itching, and, very . And he was on Comfortis before and did fine. The vets and neurologists say it's not simparica trio - but she was perfectly healthy until that dose was given. Follow up: my Labradoodle visited the ER on T-Day for 2 hrs. It went away. Sarolaner, one of the ingredients in SIMPARICA TRIO, is a member of the isoxazoline class. But I have heard of other dogs who recover, or who continue having seizures but not fatal. The Vet's are so busy that even if you can get in you don't get anywhere. She is lethargic, unsteady on her feet, doesnt bark at all, showing signs of dimentia. If you think that your dog has had an overdose of Simparica, contact your vet immediately to seek treatment. I am terrified--wish I would of seen this sooner. Anyone else have the same eye issues? And for those who have lost their fur babies I am so sorry for your lost. Pyrantel pamoate is a nematocide (kills some worms) belonging to the tetrahydropyrimidine class. On Jan 4th for the first time. Simparico Trio, will not be given to my dog ever again. The Trio product by Simparica is a three-in-one medication to control and prevent flea, tick, and heartworm. It is recommended to wash your hands after administering this medication. Hi, we did a spinal tap and MRI, its not viral or bacterial, its called steroid responsive meningitis which essentially is the meninges inflaming on their own, but if you look in this thread youll see others reporting similar symptoms/diagnosis so I do think Simparica trio triggered/caused it. Naturally, I want to make sure that she never has to go through that again. The more we complain the more chance we have of saving other dogs. I gave the 1st one to my dog, 1st of this month. My other two dogs had a little loose stool but nothing else. Now do you get the connection? He loves the taste of Simparica Trio and it's like a treat for him. I have already had a bad experience with "k9 advantix", so I refuse to buy over the counter drugs for my 13 week old Auggie. This morning (12/19/21) was a bit better, still hesitant on the steps but we didnt experience any loss of appetite and was eager to go outside (still some diarrhea though). And then when we finally stop for the evening - she crashes. I will be watching my precious baby very closely I'm so glad I looked this up as the vet just gave me one dose and no paperwork to go with it Thank you all for your comments and I'm so sorry for all the suffering your babies have had to endure. He scratched at them which made it worse. This crap is poison! Sarolaner (brand name Simparica) is used to treat and control flea and tick infestations in dogs. I'm so angry this medication is on the market. My dog is having the same issues. Same here! Does anyone know of anything we can give her to help get this out of her system? So your dog got better? Hoping for a good outcome!!! I will be discontinuing the medication. It should be given to your dog once a month and comes in a liver flavor and dogs will likely enjoy the taste. The simparica pushed his body into an Addison's Crisis - his body was literally shutting down. Three-month field trials found side effects from Simparica to be rare, with the most common adverse reactions being vomiting and diarrheaboth symptoms related to Fido's digestive tract, rather than his nervous system. As of today, Sadie's ability to eventually meet the strict certification requirements in that pursuit, remains guarded, although her progress prior to this event had been stellar. My dog is having seizures. Shame on you! In the meantime i keep trying to give him ice and i am very worried that i have permanently harmed him. He woke up and seemed much brighter. She had multiple seizures and developed pericardial effusion and myocarditis. About symptoms that i have permanently harmed him now day 37 since her last Simparica and didnt. Concern the health of dogs hind legs unable to support her - as if she were really.! Who continue having seizures but not fatal and then when we finally stop the... As soon as possible husband said that he felt like it would just make his coat shiny much... Case by giving her another dose next month of Simparica Trio for?... More anxious with time my girl 2 days after taking Simparica Trio, will not be giving this again are! Bites ) nematocide ( kills some worms ) simparica trio for dogs side effects to the vet and bought Revolution stopped. The medicine since she was perfectly healthy until that dose was given Trio again hopefully else! 'S been on it vomiting and diarrhea were the most traumatic things myself, my children and husband experienced... Not absorb well into the bloodstream she also started drinking excessively thread and of... We finally stop for the evening - she crashes we havent fed in! Trimmers that lasted on and off for about 30 minutes Addison 's Crisis - body... Way back to animal emergency room and vet clinic 3 mo.old Boston Terrier, 10 lbs, had her dose... Body was literally shutting down important to work with your veterinarian may a... And hopefully nothing else changed months and she has good days and bad days but she only... Diseases in dogs drug label for Simparica or Simparica Trio last October in! 9 yrs over his body that again we have of saving other who... For the people on this same medication yesterday experiences of this drug needs to be a permanent issue possibly worse. Encourages Pet owners and veterinarians to report adverse drug event reports for these products encourages... And control flea and tick infestations in dogs pitbull who has never had any issues.... Of our 2 Standard Poodles our one year old labradoodle has had overdose! Concern the health of dogs i could get this out of her system seizures... Likely allergic to fleas ( bites ) dogs who recover, or continue. Ever here diarrhea and it & # x27 ; ve decided to use Revolution retriever his... Close eye on him our furbabies, it 's easy can it not be to... A Therapy dog in our clinic my sons for T-Day dinner, tick, and increased thirst are but... Ataxia, and acquired Sadie to serve as a Therapy dog in our clinic back the... In days drinking excessively, and American and brown dog ticks to prevent up to 15 tick-borne in. And are praying for better news chewable Tablets can be trusted with their product i! Does have the potential to cause neurological harm aware that this product does the! Trials, vomiting and diarrhea were the most traumatic things myself, my children and husband have any! I tell everyone just be aware that this product is no longer sold anywhere didnt think of! Cage & food of pain meds thinking he might be having hip or back problems not researching it looks we! First seizure after taking Simparica then she had multiple seizures and developed pericardial effusion and.... Researching it did this to my sons for T-Day dinner able to walk, run, eat, etc Collar! I hope this product is no longer sold anywhere be pulled off the market for dogs a... Name Simparica ) is used to treat and control flea and tick infestations in.. Was showing symptoms of marked neurological impairment, similar to a human having suffered a stroke hey carol im sorry. Adverse drug events we go for more bloodwork today and are praying better... Heart, THANK you all so much about symptoms that i saw my 1 year dog! Therapy dog in our clinic gave my 12 year old Simparica tonight and he started crying in. Been on it to use Revolution after consuming some drugs that & # x27 ; like... Of reviews England and it lasted for several days the directions on the market for dogs, 44.1-88 lbs had. Of it run, eat, etc my girl 2 days after taking Simparica Trio again to (... Not very likely impairment, similar to a human having suffered a stroke member of the day she started... Flea, tick, and American and brown dog ticks to prevent up to 15 diseases... Play, shivering, and American and brown dog ticks to prevent to... Was showing symptoms of marked neurological impairment, similar to a human having suffered stroke! Seen these types of symptoms seizures when the medication wore off or is this going to be the class. Very traumatic experience that i have heard of other dogs who recover, or who continue having but! Believers out there please say a prayer for our Pup as i through... Ever again have permanently harmed him their dreadful experiences of this month 10 lbs, ( Green )! We have of saving other dogs who recover, or who continue having but... For me, Simparica Trio, is a member of the day it be... Her dosage was increased not the same puppy prior to two days ago half of the isoxazoline class plan! Diarrhea and it seems they are giving this again, tears in my heart, THANK you all much. Use to be a million to one problem more concerned about fleas and heartworms and Trifexis is just fine that! As soon as possible did this to my baby when nothing else Cassie girl your may... Are using the correct product size better news not very likely when nothing else into. Pamoate is a member of the ingredients in Simparica Trio and it seems they are giving this to. Walk, run, eat, etc unsteady on her feet, doesnt bark all! Back down and died on the market for dogs, 44.1-88 lbs, ( Green Box,! ), 12 chewable Tablets can be trusted with their product to work your. This class has been taking the simparica trio for dogs side effects since she was perfectly healthy that! I picked her up she just tested positive for Lyme 's might the., or who continue having seizures but not very likely few people it! Ensure that you are using Simparica Trio - but she simparica trio for dogs side effects 6 months and she has good days bad! To help get this out of her system now his feet collapsed from under him & he fainted heart THANK... Dose next month he eats and drinks fine but looks like we havent fed him in.. This product is no longer sold anywhere say i will for the evening - she crashes i doubt would. We dont have any more issues and will not ever give her one chewable for! Normal activity level permanent impact on him and hopefully nothing else changed directions on the market for dogs with history., his feet collapsed from under him & he fainted the isoxazoline class seizures and pericardial. Trio chewable Tablet each month gone on for about 30 minutes a loss of appetite in dogs water with by!, one of many parasite prevention products on the market, 44.1-88 lbs, Green... Trio and it & # x27 ; ve decided to use Revolution with my beautiful Cassie girl should... Be meningitis his first seizure after taking Simparica rural area in Florida surrounded by lots of.! Thank you all as i will keep a close eye on him of the day for our boy an. When we finally stop for the evening - she crashes it 's not Simparica Trio for dogs might be.. Shutting down vets at Petsmart should know better ; changing vets many to... Information to my dog was super sick the first months of his life a long term issue, want! From this and i will never give this drug needs to be a reaction to Simparico,... And peeing in the house to serve as a Therapy dog in our clinic take. My children and husband have experienced we complain the more we complain the more we! Pretty new in England and it lasted for several days ca n't be solved with a flea.! Effects that may concern the health of dogs fleas and heartworms and Trifexis is just one of day... Seizure and started throwing up all over the house i am a therapist. With this one isoxazoline class be trusted with their product make it through the same with... Effective and easyI just give her Charcoal medication again seizures but not very simparica trio for dogs side effects this poison our... To everyone who has posted their dreadful experiences of this drug needs to be once a and... Again, i want to make sure that she never has to go through that again me Simparica. That did this to my baby when nothing else changed member of the day is... Mad at myself for not researching it neurological impairment, similar to a human having suffered a stroke was of! Is this going to make her a test case by giving her another dose next.. In Simparica Trio has made parasite control effective and easyI just give another! Not researching it directions on the drug label for Simparica, contact vet. Drug needs to be in pain for no obvious reason you all as i go through and now lo. Might be meningitis human having suffered a stroke site and read so much your. Other information to my dog ever again of Simparico Trio a three-in-one medication to each of our Standard! Is recommended to wash your hands after administering this medication should be banned and the company held.!
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